Introduction: Teeth with Irreversible Pulpitis usually undergo root canal therapy (RCT). This treatment modality is often considered disadvantageous as it removes vital pulp tissue and weakens the tooth structure. A relatively new concept has risen which suggests vital pulp therapy (VPT) for Irreversible Pulpitis. VPT with calcium enriched mixture (VPT/CEM) has demonstrated favorable treatment outcomes when treating permanent molars with Irreversible Pulpitis. This study aims to compare patient related factors, safety and organizational consideration as parts of health technology assessment (HTA) of the new VPT/CEM biotechnology when compared with RCT.Materials and Methods: Patient related factors were assessed by looking at short- and long-term clinical success; safety related factors were evaluated by a specialist committee and discussion board involved in formulating healthcare policies. Organizational evaluation was performed and the social implications were assessed by estimating the costs, availability, accessibility and acceptability. The impact of VPT/CEM biotechnology was assessed by investigating the incidence of Irreversible Pulpitis and the effect of this treatment on reducing the burden of disease.Results: VPT/CEM biotechnology was deemed feasible and acceptable like RCT; however, it was more successful, accessible, affordable, available and also safer than RCT.Conclusion: When considering socioeconomic implications on oral health status and oral health-related quality of life of VPT/CEM, the novel biotechnology can be more effective and more efficient than RCT in mature permanent molars with Irreversible Pulpitis.

Dear Readers, In the ever-evolving landscape of endodontics, critical deliberations that challenge traditional perceptions, concepts and terminologies are essential to drive progress. One important discussion, that has garnered significant attention in recent times, is the nomenclature of Irreversible Pulpitis (IP)....

Background/purpose: Mineral Trioxide Aggregate (MTA) has become integral in endodontics, particularly in addressing Irreversible Pulpitis due to its notable biocompatibility and sealing properties. This bibliometrics and scientometric study aims to systematically analyse the literature to identify critical trends, influential publications, and emerging research areas.Materials and methods: Publications were acquired online from the PubMed and Scopus databases on December 7th, 2023. Then, studies were screened based on title and abstract and irrelevant studies were eliminated. The publication output was then analyzed using Google Sheet, R package's Bibliometrix (Biblioshiny), and VOSviewer.Results: From 136 studies, 60 studies were included. The study highlights a substantial annual growth rate of 18.02%. Collaboration emerges as a prominent feature, with an average of 4.78 co-authors per document and 21.67% of collaborations being international, with India standing out as the most prominent contributing country. Recent trends indicate a surge in investigating diverse conditions, exploring advanced material combinations, and a growing interest in decision-making frameworks within endodontic practices. Several topics are still less developed, including other materials, decision-making frameworks, special consideration for specific patient populations, and the role of medical informatics.Conclusion: This study elucidates the dynamic evolution of research priorities in MTA and Irreversible Pulpitis, emphasizing key trends and areas for further exploration and development.

Background. The present study evaluated the clinical and radiographic outcomes of Biodentine pulpotomy for 24 months in symptomatic vital mature permanent teeth with caries exposure. Methods. Seventy-three patients with a chief complaint of spontaneous pain in permanent teeth were screened. Finally, 47 mature permanent teeth underwent a Biodentine pulpotomy procedure. Clinical evaluation of 47 teeth was carried out at 1, 3, 6, 9, 12, and 24 months and radiographic evaluations were made at 6, 12, and 24 months. The success of Biodentine pulpotomy was evaluated using Pearson’, s chi-square test. The significance level was determined at P < 0. 05. Results. At 24 months, the clinical and radiographic success rate was 97. 78%, with only one clinical failure at 9 months. Conclusion. The clinical and radiographic success of Biodentine pulpotomy was high (97. 78%). Thus, Biodentine pulpotomy can be an alternative to root canal treatment (RCT) in symptomatic vital mature permanent teeth.